Download Alligator Metabolism Studies on Chemical Reactions in Vivo by Roland A. Coulson, Thomas Hernandez PDF

By Roland A. Coulson, Thomas Hernandez

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Extra info for Alligator Metabolism Studies on Chemical Reactions in Vivo

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693//c, is not con­ stant as its value varies with half-life, but X, the rate constant corrected for variations in blood flow, is truly constant. Reactions affected by blood flow In a live vertebrate, the rate of a reaction may be increased by increasing the substrate concentration or by increasing the rate of blood flow, or by both. In the reaction V = K[S]F, both [S] and F would appear to be of equal importance in influencing reac­ tion rate. In fact, intolerance to great osmotic press- 30 ROLAND A.

Each species was injected with 18 different amino xacids, the rate of disappearance from the plasma was plotted, and the catabolic rate in (%)/min was calculated. The amino acid dose was 10mmol/kg. Frequent handling of the rats would necessarily increase the metabolic rate over the "resting" value shown in the figure, so an increase in metabolic rate over the "resting" of 80% was assumed. The rats weighed about 250 g, the dogs, 10 kg, the chameleons, 6g, and the alligators and turtles, 1 kg. The reptiles were at 28°C.

35 kg of protein each hour for 24 hr if he continued in the resting state, and more than that if he exercised. The high rate of blood flow would aid in removal of the released amino acids, but even that aid to effi­ ciency would appear inadequate to explain the incred­ ible rate of digestion (Coulson & Herbert, 1981). Per­ haps the fact that the shrew is so small accounts for the efficiency as the smallness of the protein bolus in the gut at any one time would permit exposure of a large fraction of the proteins to enzyme action.

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